Evolución y niveles de colesterol

Esto es extraordinariamente interesante. Si los seres vivos evolucionan hacia aquellas características más favorables para la supervivencia, extinguéndose progresivamente las menos favorables (sobre todo las que te conducen a un ataque al corazón, lo que paraliza tu descendencia ipso facto)… ¿como es posible que el ser humano de manera universal tenga algo en su sangre que amenaza la vida de manera tan letal? Uno de los supuestos es que los cazadores recolectores tenían niveles más bajos de colesterol que nosotros, pero no estoy muy seguro de que esto sea así. El primer paper sobre nutrición evolutiva parece ser este

Un blog discute sobre todo esto, es interesante

Did Hunter-Gatherers Have Low Serum Cholesterol?

The caption states that total cholesterol (TC) ranges between 70 and 140 mg/dl in hunter-gatherers, and LDL cholesterol (LDL-C) between 35 and 70 mg/dl. However, this claim is unsourced.

The claim that healthy hunter-gatherers had serum cholesterol below 140 mg/dl is quite surprising, given that contemporary populations are healthiest when their serum cholesterol is over 200 mg/dl, and mortality rises and life expectancy falls sharply as serum cholesterol falls below 180 mg/dl

Are hunter-gatherers – either their diets or their genetics – so different from modern populations? Or is the claim that healthy hunter-gatherers have low serum cholesterol a mistake?

Serum Cholesterol Among Hunter-Gatherers: Conclusion

Overall I think the data should dispose us to look toward infectious burden, rather than genetics or diet, as the primary determinant of serum cholesterol among hunter-gatherers. If genetic differences influence mean TC among hunter-gatherer populations, it is probably because of evolutionary adaptations to local pathogens, such as the heavy parasite burden in sub-Saharan Africa.